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AMD Instinct MI100 vs AMD Instinct MI350P: Comparison
AMD Instinct MI100 and AMD Instinct MI350P separate most on memory size: AMD Instinct MI100 at 32 GB, AMD Instinct MI350P at 144 GB, 78% in favour of AMD Instinct MI350P. Memory Bandwidth splits them by another 70%, again favouring AMD Instinct MI350P. They match on 5 other specifications, including gpu brand, board partner and form factor.
Specs
| Specification | ![]() | ![]() |
|---|---|---|
| GPU Brand | AMD | AMD |
| Series | Instinct MI100 Series | Instinct MI350 Series |
| Board Partner | AMD (Reference) | AMD (Reference) |
| Memory Type | HBM2 | HBM3E |
| TDP | 300W Peak | 600W TBP (Max); 450W TBP configurable |
| Architecture | CDNA | CDNA4 |
| Memory Bandwidth | 1200 GB/s-70% | 4000 GB/s |
| Form Factor | PCIe Add-in Card | PCIe Add-in Card |
| Lithography | TSMC 7nm FinFET | TSMC 3nm | 6nm FinFET |
| Compute Units | 120 | 128 |
| Stream Processors | 7,680 | 8,192 |
| Peak Engine Clock | 1502 MHz | 2200 MHz |
| Memory Size | 32 GB-78% | 144 GB |
| Memory ECC Support | Yes (Full-Chip) | Yes (Full-Chip) |
| PCIe Interface | PCIe 4.0 x16 , PCIe 3.0 x16 | PCIe 5.0 x16 |
| Cooling | Passive | Passive |




