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AMD Instinct MI100 vs NVIDIA RTX PRO 4000 Blackwell SFF: Comparison
AMD Instinct MI100 and NVIDIA RTX PRO 4000 Blackwell SFF separate most on memory bandwidth: AMD Instinct MI100 at 1200 GB/s, NVIDIA RTX PRO 4000 Blackwell SFF at 672 GB/s, 44% in favour of AMD Instinct MI100.
Specs
| Specification | ![]() | ![]() |
|---|---|---|
| GPU Brand | AMD | NVIDIA |
| Series | Instinct MI100 Series | RTX PRO Blackwell |
| Board Partner | AMD (Reference) | NVIDIA Reference (workstation, no AIB partners) |
| Memory Type | HBM2 | GDDR7 |
| TDP | 300W Peak | 70 W |
| Architecture | CDNA | Blackwell |
| Memory Bandwidth | 1200 GB/s | 672 GB/s-44% |
| Launch Date | 11/16/2020 | 2025-04 |
| PCIe Interface | PCIe 4.0 x16 , PCIe 3.0 x16 | PCIe 5.0 x8 |
Verdict
NVIDIA RTX PRO 4000 Blackwell SFF
7.7 / 10 Expert Rating
A genuinely useful niche card - the only realistic way to get 24GB of workstation VRAM into a truly small chassis.




