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AMD Instinct MI100 vs NVIDIA RTX PRO 5000 72GB Blackwell: Comparison
AMD Instinct MI100 and NVIDIA RTX PRO 5000 72GB Blackwell separate most on memory bandwidth: AMD Instinct MI100 at 1200 GB/s, NVIDIA RTX PRO 5000 72GB Blackwell at 1344 GB/s, 11% in favour of NVIDIA RTX PRO 5000 72GB Blackwell.
Specs
| Specification |  |  |
|---|---|---|
| GPU Brand | AMD | NVIDIA |
| Series | Instinct MI100 Series | RTX PRO Blackwell |
| Board Partner | AMD (Reference) | NVIDIA Reference (workstation, no AIB partners) |
| Memory Type | HBM2 | GDDR7 |
| TDP | 300W Peak | 300 W |
| Architecture | CDNA | Blackwell |
| Memory Bandwidth | 1200 GB/s-11% | 1344 GB/s |
| Launch Date | 11/16/2020 | 2025-09 |
| PCIe Interface | PCIe 4.0 x16 , PCIe 3.0 x16 | PCIe 5.0 x16 |
Verdict
NVIDIA RTX PRO 5000 72GB Blackwell
8.8 / 10 Expert Rating
A smart memory-capacity-focused variant - genuinely useful for teams whose bottleneck is VRAM rather than compute, at meaningfully lower power draw than the flagship.