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AMD Instinct MI100 vs NVIDIA Quadro RTX 8000: Comparison
AMD Instinct MI100 and NVIDIA Quadro RTX 8000 differ on memory type: AMD Instinct MI100 at HBM2, NVIDIA Quadro RTX 8000 at GDDR6, which puts NVIDIA Quadro RTX 8000 ahead on that measure.
Specs
| Specification | ![]() | ![]() |
|---|---|---|
| GPU Brand | AMD | NVIDIA |
| Series | Instinct MI100 Series | Quadro RTX |
| Board Partner | AMD (Reference) | PNY / NVIDIA Reference |
| Memory Type | HBM2 | GDDR6 |
| TDP | 300W Peak | 260 W |
| Architecture | CDNA | Turing |
| Memory ECC Support | Yes (Full-Chip) | Yes |
| PCIe Interface | PCIe 4.0 x16 , PCIe 3.0 x16 | PCIe 3.0 x16 |
Verdict
NVIDIA Quadro RTX 8000
6 / 10 Expert Rating
Legacy flagship whose sole remaining selling point is VRAM capacity; a used bargain for memory-bound pro work, a poor choice for anything compute-bound.




