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AMD Instinct MI100 vs NVIDIA RTX PRO 6000 Blackwell Server Edition: Comparison
AMD Instinct MI100 and NVIDIA RTX PRO 6000 Blackwell Server Edition separate most on memory bandwidth: AMD Instinct MI100 at 1200 GB/s, NVIDIA RTX PRO 6000 Blackwell Server Edition at 1792 GB/s, 33% in favour of NVIDIA RTX PRO 6000 Blackwell Server Edition.
Specs
| Specification | ![]() | ![]() |
|---|---|---|
| GPU Brand | AMD | NVIDIA |
| Series | Instinct MI100 Series | RTX PRO Blackwell |
| Board Partner | AMD (Reference) | NVIDIA Reference (OEM server/rackmount, passive cooling) |
| Memory Type | HBM2 | GDDR7 |
| TDP | 300W Peak | 600 W |
| Architecture | CDNA | Blackwell |
| Memory Bandwidth | 1200 GB/s-33% | 1792 GB/s |
| Launch Date | 11/16/2020 | 2025-05 |
| PCIe Interface | PCIe 4.0 x16 , PCIe 3.0 x16 | PCIe 5.0 x16 |
Verdict
NVIDIA RTX PRO 6000 Blackwell Server Edition
9.4 / 10 Expert Rating
The most VRAM-dense Blackwell professional GPU NVIDIA sells outside the B-series data center parts - a serious tool for AI infrastructure teams, wasted in a single desktop.




