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AMD Instinct MI210 vs AMD Radeon Pro W6800X: Comparison
AMD Instinct MI210 and AMD Radeon Pro W6800X separate most on memory bus width: AMD Instinct MI210 at 4096 bit, AMD Radeon Pro W6800X at 256 bit, 94% in favour of AMD Instinct MI210. VRAM splits them by another 50%, again favouring AMD Instinct MI210. They match on gpu brand and card length.
Specs
| Specification | ![]() | ![]() |
|---|---|---|
| GPU Brand | AMD | AMD |
| Series | Instinct MI200 | Radeon Pro W6000 |
| Board Partner | AMD Reference (PCIe dual-slot card, data center/OEM only) | Apple (Mac Pro exclusive) |
| VRAM | 64 GB | 32 GB-50% |
| Tier | Datacenter / AI Accelerator | High-End |
| Memory Type | HBM2E | GDDR6 |
| Boost Clock | 1700 MHz-16% | 2015 MHz |
| Ray Tracing Support | false | true |
| TDP | 300 W-20% | 250 W |
| Architecture | CDNA 2 (single Graphics Compute Die) | RDNA 2 |
| Card Length | 267 mm | 267 mm |
| Slot Width | 2 (dual-slot, passive cooling for server airflow) | 2 |
| Memory Bus Width | 4096 bit | 256 bit-94% |
| Compute Units | 104 CUs | 60 |
| PCIe Interface | PCIe 4.0 x16 | PCIe 4.0 x16 (MPX connector) |
| Display Outputs | N/A - compute-only, no display output | 6x Mini-DisplayPort 1.4 (via MPX Module) |
Verdict
AMD Instinct MI210
7.3 / 10 Expert Rating
A practical, PCIe-slot-friendly way to get CDNA 2 compute into a standard server, useful for smaller HPC and AI deployments, but clearly the entry point of its generation next to the dual-die MI250X and now well behind the MI300 series.
AMD Radeon Pro W6800X
6.2 / 10 Expert Rating
A sensible mid-tier Mac Pro GPU option offering the same VRAM as the flagship for less; still platform-locked with no upgrade path outside that one machine.




