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AMD Instinct MI210 vs AMD Radeon RX 6750 GRE: Comparison
AMD Instinct MI210 and AMD Radeon RX 6750 GRE separate most on memory bus width: AMD Instinct MI210 at 4096 bit, AMD Radeon RX 6750 GRE at 192 bit, 95% in favour of AMD Instinct MI210. VRAM splits them by another 81%, again favouring AMD Instinct MI210. They match on gpu brand, card length and pcie interface.
Specs
| Specification | ![]() | ![]() |
|---|---|---|
| GPU Brand | AMD | AMD |
| Series | Instinct MI200 | Radeon RX 6000 |
| Board Partner | AMD Reference (PCIe dual-slot card, data center/OEM only) | AMD Reference (China OEM/retail market card) |
| VRAM | 64 GB | 12 GB-81% |
| Tier | Datacenter / AI Accelerator | Mainstream |
| Memory Type | HBM2E | GDDR6 |
| Boost Clock | 1700 MHz-21% | 2153 MHz |
| Ray Tracing Support | false | true |
| TDP | 300 W-36% | 220 W |
| Architecture | CDNA 2 (single Graphics Compute Die) | RDNA 2 |
| Card Length | 267 mm | 267 mm |
| Slot Width | 2 (dual-slot, passive cooling for server airflow) | 2 |
| Memory Bus Width | 4096 bit | 192 bit-95% |
| PCIe Interface | PCIe 4.0 x16 | PCIe 4.0 x16 |
| Display Outputs | N/A - compute-only, no display output | 1x HDMI 2.1, 3x DisplayPort 1.4 |
Verdict
AMD Instinct MI210
7.3 / 10 Expert Rating
A practical, PCIe-slot-friendly way to get CDNA 2 compute into a standard server, useful for smaller HPC and AI deployments, but clearly the entry point of its generation next to the dual-die MI250X and now well behind the MI300 series.
AMD Radeon RX 6750 GRE
6.3 / 10 Expert Rating
A conservatively-clocked GRE revision that performs a notch below the refreshed 12GB SKU; buy on price, not on the model name alone.




