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AMD Instinct MI210 vs NVIDIA Quadro RTX 6000: Comparison
AMD Instinct MI210 and NVIDIA Quadro RTX 6000 separate most on memory bus width: AMD Instinct MI210 at 4096 bit, NVIDIA Quadro RTX 6000 at 384 bit, 91% in favour of AMD Instinct MI210. VRAM splits them by another 63%, again favouring AMD Instinct MI210.
Specs
| Specification | ![]() | ![]() |
|---|---|---|
| GPU Brand | AMD | NVIDIA |
| Series | Instinct MI200 | Quadro RTX |
| Board Partner | AMD Reference (PCIe dual-slot card, data center/OEM only) | PNY / NVIDIA Reference |
| VRAM | 64 GB | 24 GB-62% |
| Tier | Datacenter / AI Accelerator | Flagship |
| Memory Type | HBM2E | GDDR6 |
| Boost Clock | 1700 MHz-4% | 1770 MHz |
| Ray Tracing Support | false | true |
| TDP | 300 W-15% | 260 W |
| Architecture | CDNA 2 (single Graphics Compute Die) | Turing |
| Card Length | 267 mm | 267 mm |
| Slot Width | 2 (dual-slot, passive cooling for server airflow) | 2 |
| Memory Bus Width | 4096 bit | 384 bit-91% |
| PCIe Interface | PCIe 4.0 x16 | PCIe 3.0 x16 |
| Display Outputs | N/A - compute-only, no display output | 4x DisplayPort 1.4, 1x VirtualLink |
Verdict
AMD Instinct MI210
7.3 / 10 Expert Rating
A practical, PCIe-slot-friendly way to get CDNA 2 compute into a standard server, useful for smaller HPC and AI deployments, but clearly the entry point of its generation next to the dual-die MI250X and now well behind the MI300 series.
NVIDIA Quadro RTX 6000
6.3 / 10 Expert Rating
The value half of NVIDIA's Turing workstation flagship pair; a solid used CAD/VFX card today, though NVIDIA's RTX PRO Ada and Blackwell cards outperform it significantly per watt.




