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AMD Instinct MI210 vs NVIDIA GeForce RTX 4080: Comparison
AMD Instinct MI210 and NVIDIA GeForce RTX 4080 separate most on vram: AMD Instinct MI210 at 64 GB, NVIDIA GeForce RTX 4080 at 16 GB, 75% in favour of AMD Instinct MI210. Boost Clock splits them by another 32%, this time favouring NVIDIA GeForce RTX 4080.
Specs
| Specification |  |  |
|---|---|---|
| GPU Brand | AMD | NVIDIA |
| Series | Instinct MI200 | GeForce RTX 40 |
| Board Partner | AMD Reference (PCIe dual-slot card, data center/OEM only) | Reference / Founders Edition |
| VRAM | 64 GB | 16 GB-75% |
| Tier | Datacenter / AI Accelerator | High-End |
| Memory Type | HBM2E | GDDR6X |
| Boost Clock | 1700 MHz-32% | 2505 MHz |
| Ray Tracing Support | false | true |
| TDP | 300 W | 320 W-7% |
| Architecture | CDNA 2 (single Graphics Compute Die) | Ada Lovelace (AD103) |
| Card Length | 267 mm | 304 mm-14% |
| Slot Width | 2 (dual-slot, passive cooling for server airflow) | 3 |
Verdict
AMD Instinct MI210
7.3 / 10 Expert Rating
A practical, PCIe-slot-friendly way to get CDNA 2 compute into a standard server, useful for smaller HPC and AI deployments, but clearly the entry point of its generation next to the dual-die MI250X and now well behind the MI300 series.
NVIDIA GeForce RTX 4080
8 / 10 Expert Rating
A solid high-end pick if its price and 16GB VRAM allocation match your target resolution.