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AMD Instinct MI210 vs NVIDIA RTX PRO 4500 Blackwell: Comparison
AMD Instinct MI210 and NVIDIA RTX PRO 4500 Blackwell separate most on memory bus width: AMD Instinct MI210 at 4096 bit, NVIDIA RTX PRO 4500 Blackwell at 256 bit, 94% in favour of AMD Instinct MI210. VRAM splits them by another 50%, again favouring AMD Instinct MI210.
Specs
| Specification |  |  |
|---|---|---|
| GPU Brand | AMD | NVIDIA |
| Series | Instinct MI200 | RTX PRO Blackwell |
| Board Partner | AMD Reference (PCIe dual-slot card, data center/OEM only) | NVIDIA Reference (workstation, no AIB partners) |
| VRAM | 64 GB | 32 GB-50% |
| Tier | Datacenter / AI Accelerator | High-End |
| Memory Type | HBM2E | GDDR7 |
| Boost Clock | 1700 MHz-29% | 2400 MHz |
| Ray Tracing Support | false | true |
| TDP | 300 W-50% | 200 W |
| Architecture | CDNA 2 (single Graphics Compute Die) | Blackwell |
| Process Node | TSMC 6nm | TSMC 4N |
| Card Length | 267 mm | 267 mm |
| Slot Width | 2 (dual-slot, passive cooling for server airflow) | 2 |
| Memory Bus Width | 4096 bit | 256 bit-94% |
| Memory Bandwidth | 1600 GB/s | 896 GB/s-44% |
| Launch Date | 2022-03 | 2025-04 |
| PCIe Interface | PCIe 4.0 x16 | PCIe 5.0 x16 |
| Display Outputs | N/A - compute-only, no display output | 4x DisplayPort 2.1b |
Verdict
AMD Instinct MI210
7.3 / 10 Expert Rating
A practical, PCIe-slot-friendly way to get CDNA 2 compute into a standard server, useful for smaller HPC and AI deployments, but clearly the entry point of its generation next to the dual-die MI250X and now well behind the MI300 series.
NVIDIA RTX PRO 4500 Blackwell
8.3 / 10 Expert Rating
A strong mid-to-high-end workstation card - the VRAM and generational uplift over Ampere-class RTX A5000/A5500 cards make it worth the jump for pro-viz and AI work.