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AMD Instinct MI210 vs NVIDIA RTX PRO 5000 72GB Blackwell: Comparison
AMD Instinct MI210 and NVIDIA RTX PRO 5000 72GB Blackwell separate most on memory bus width: AMD Instinct MI210 at 4096 bit, NVIDIA RTX PRO 5000 72GB Blackwell at 384 bit, 91% in favour of AMD Instinct MI210. Boost Clock splits them by another 29%, this time favouring NVIDIA RTX PRO 5000 72GB Blackwell. They match on tdp and card length.
Specs
| Specification |  |  |
|---|---|---|
| GPU Brand | AMD | NVIDIA |
| Series | Instinct MI200 | RTX PRO Blackwell |
| Board Partner | AMD Reference (PCIe dual-slot card, data center/OEM only) | NVIDIA Reference (workstation, no AIB partners) |
| VRAM | 64 GB-11% | 72 GB |
| Tier | Datacenter / AI Accelerator | Flagship |
| Memory Type | HBM2E | GDDR7 |
| Boost Clock | 1700 MHz-29% | 2410 MHz |
| Ray Tracing Support | false | true |
| TDP | 300 W | 300 W |
| Architecture | CDNA 2 (single Graphics Compute Die) | Blackwell |
| Process Node | TSMC 6nm | TSMC 4N |
| Card Length | 267 mm | 267 mm |
| Slot Width | 2 (dual-slot, passive cooling for server airflow) | 2 |
| Memory Bus Width | 4096 bit | 384 bit-91% |
| Memory Bandwidth | 1600 GB/s | 1344 GB/s-16% |
| Launch Date | 2022-03 | 2025-09 |
| PCIe Interface | PCIe 4.0 x16 | PCIe 5.0 x16 |
| Display Outputs | N/A - compute-only, no display output | 4x DisplayPort 2.1b |
Verdict
AMD Instinct MI210
7.3 / 10 Expert Rating
A practical, PCIe-slot-friendly way to get CDNA 2 compute into a standard server, useful for smaller HPC and AI deployments, but clearly the entry point of its generation next to the dual-die MI250X and now well behind the MI300 series.
NVIDIA RTX PRO 5000 72GB Blackwell
8.8 / 10 Expert Rating
A smart memory-capacity-focused variant - genuinely useful for teams whose bottleneck is VRAM rather than compute, at meaningfully lower power draw than the flagship.