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AMD Instinct MI210 vs AMD Radeon Pro WX 9100: Comparison
AMD Instinct MI210 and AMD Radeon Pro WX 9100 separate most on vram: AMD Instinct MI210 at 64 GB, AMD Radeon Pro WX 9100 at 16 GB, 75% in favor of AMD Instinct MI210. Memory Bandwidth splits them by another 70%, again favoring AMD Instinct MI210. They match on gpu brand and card length.
Pick the AMD Instinct MI210 if that matters to you: 4x the VRAM (64 GB vs 16 GB), which matters at 1440p and 4K with high texture settings. Pick the AMD Radeon Pro WX 9100 if that matters to you: 23% lower TDP (230 W vs 300 W), so it needs a smaller power supply and runs cooler.
Which is better, AMD Instinct MI210 or AMD Radeon Pro WX 9100?
On paper, AMD Instinct MI210 has the edge on vram, at 64 GB vs AMD Radeon Pro WX 9100 at 16 GB.
What is the main difference between AMD Instinct MI210 and AMD Radeon Pro WX 9100?
The AMD Instinct MI210 and AMD Radeon Pro WX 9100 are built for different jobs. The AMD Instinct MI210 has 4x the VRAM (64 GB vs 16 GB), which matters at 1440p and 4K with high texture settings. The AMD Radeon Pro WX 9100 has 23% lower TDP (230 W vs 300 W), so it needs a smaller power supply and runs cooler.
Specs and benchmarks
GPU Brand
- AMD Instinct MI210
- AMD
- AMD Radeon Pro WX 9100
- AMD
Series
- AMD Instinct MI210
- Instinct MI200
- AMD Radeon Pro WX 9100
- Radeon PRO WX x100 Series
Board Partner
- AMD Instinct MI210
- AMD Reference (PCIe dual-slot card, data center/OEM only)
- AMD Radeon Pro WX 9100
- AMD (Reference)
VRAM
- AMD Instinct MI210
- 64 GBBest
- AMD Radeon Pro WX 9100
- 16 GB-75%
Tier
- AMD Instinct MI210
- Datacenter / AI Accelerator
- AMD Radeon Pro WX 9100
- Workstation
Memory Type
- AMD Instinct MI210
- HBM2E
- AMD Radeon Pro WX 9100
- HBM2
TDP
- AMD Instinct MI210
- 300 W-30%
- AMD Radeon Pro WX 9100
- 230 WBest
Architecture
- AMD Instinct MI210
- CDNA 2 (single Graphics Compute Die)
- AMD Radeon Pro WX 9100
- Vega
Card Length
- AMD Instinct MI210
- 267 mm
- AMD Radeon Pro WX 9100
- 267 mm
Compute Blocks
- AMD Instinct MI210
- 104
- AMD Radeon Pro WX 9100
- 64
Memory Bus Width
- AMD Instinct MI210
- 4096 bitBest
- AMD Radeon Pro WX 9100
- 2048 bit-50%
Memory Bandwidth
- AMD Instinct MI210
- 1600 GB/sBest
- AMD Radeon Pro WX 9100
- 484 GB/s-70%
PCIe Generation
- AMD Instinct MI210
- PCIe 4.0 x16
- AMD Radeon Pro WX 9100
- PCIe 3.0 x16
Launch Date
- AMD Instinct MI210
- 2022-03
- AMD Radeon Pro WX 9100
- August 2017
Which one should you pick?
Choose AMD Instinct MI210 if you want the higher VRAM (64 GB vs 16 GB), the lower card length (267 mm vs 267 mm) and the higher memory bus width (4096 bit vs 2048 bit).
Choose AMD Radeon Pro WX 9100 if you want the lower TDP (230 W vs 300 W).
Verdict
AMD Instinct MI210
7.3 / 10 Expert Rating
A practical, PCIe-slot-friendly way to get CDNA 2 compute into a standard server, useful for smaller HPC and AI deployments, but clearly the entry point of its generation next to the dual-die MI250X and now well behind the MI300 series.




