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AMD Instinct MI250 vs AMD Radeon Pro W6800X: Comparison
AMD Instinct MI250 and AMD Radeon Pro W6800X differ on memory type: AMD Instinct MI250 at HBM2E, AMD Radeon Pro W6800X at GDDR6, which puts AMD Radeon Pro W6800X ahead on that measure.
Specs
| Specification | ![]() | ![]() |
|---|---|---|
| GPU Brand | AMD | AMD |
| Series | Instinct MI200 Series | Radeon Pro W6000 |
| Board Partner | AMD (Reference) | Apple (Mac Pro exclusive) |
| Memory Type | HBM2E | GDDR6 |
| TDP | 500W | 560W Peak | 250 W |
| Architecture | CDNA2 | RDNA 2 |
| Compute Units | 208 | 60 |
| Stream Processors | 13,312 | 3840 |
| PCIe Interface | PCIe 4.0 x16 | PCIe 4.0 x16 (MPX connector) |
Verdict
AMD Radeon Pro W6800X
6.2 / 10 Expert Rating
A sensible mid-tier Mac Pro GPU option offering the same VRAM as the flagship for less; still platform-locked with no upgrade path outside that one machine.




