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AMD Instinct MI250 vs AMD Radeon RX 6500 XT: Comparison

Instinct MI250 vs Radeon RX 6500 XT: the tdp difference

The gap that matters here is tdp: Instinct MI250 500 W against Radeon RX 6500 XT 107 W, which puts Radeon RX 6500 XT 367% ahead. Memory bandwidth runs the same way, 3200 GB/s on the Instinct MI250 versus 144 GB/s on the Radeon RX 6500 XT, another win for Instinct MI250. Boost clock runs the same way, 1700 MHz on the Instinct MI250 versus 2815 MHz on the Radeon RX 6500 XT, another win for Radeon RX 6500 XT. Instinct MI250 also leads on memory bus width, 8192 bit on the Instinct MI250 versus 64 bit on the Radeon RX 6500 XT.

Which should you buy, Instinct MI250 or Radeon RX 6500 XT?

The Instinct MI250 is the one to take for buyers comparing AMD's official reference specifications and researching a chip before choosing a board-partner card, though it is not the pick for overclocking-focused enthusiasts (reference clocks only). Avoid it for buyers wanting a specific retail card with cooler and warranty details. The Radeon RX 6500 XT suits gamers targeting the resolution this entry-level tier is built for, though it is the wrong buy for 4K/high-refresh gamers if this card's tier sits below High-End. The same goes for builders who want 4GB of VRAM without moving up a tier. It is not the one for buyers who need the absolute best price-to-performance and should compare street prices first. Our rating of the Radeon RX 6500 XT (5.5/10): A solid entry-level pick if its price and 4GB VRAM allocation match your target resolution.

Frequently asked questions

Do the Instinct MI250 and Radeon RX 6500 XT differ on board partner?

Yes. Board Partner reads Reference on the Instinct MI250 versus AMD Reference on the Radeon RX 6500 XT.

Is the GPU Brand the same on the Instinct MI250 and Radeon RX 6500 XT?

It is. Both are listed at AMD, so it is not a reason to pick one over the other.

Specs and benchmarks

  • GPU Brand

    AMD Instinct MI250
    AMD
    AMD Radeon RX 6500 XT
    AMD
  • Series

    AMD Instinct MI250
    Instinct
    AMD Radeon RX 6500 XT
    Radeon RX 6000
  • Board Partner

    AMD Instinct MI250
    Reference
    AMD Radeon RX 6500 XT
    AMD Reference
  • Tier

    AMD Instinct MI250
    Datacenter
    AMD Radeon RX 6500 XT
    Entry-Level
  • Memory Type

    AMD Instinct MI250
    HBM2E
    AMD Radeon RX 6500 XT
    GDDR6Best
  • Boost Clock

    AMD Instinct MI250
    1700 MHz-40%
    AMD Radeon RX 6500 XT
    2815 MHzBest
  • TDP

    AMD Instinct MI250
    500 W-367%
    AMD Radeon RX 6500 XT
    107 WBest
  • Architecture

    AMD Instinct MI250
    CDNA2
    AMD Radeon RX 6500 XT
    RDNA 2 (Navi 24)
  • Slot Width

    AMD Instinct MI250
    Not Applicable
    AMD Radeon RX 6500 XT
    2
  • Shader Units

    AMD Instinct MI250
    13312
    AMD Radeon RX 6500 XT
    1024
  • Memory Bus Width

    AMD Instinct MI250
    8192 bitBest
    AMD Radeon RX 6500 XT
    64 bit-99%
  • Memory Bandwidth

    AMD Instinct MI250
    3200 GB/sBest
    AMD Radeon RX 6500 XT
    144 GB/s-95%
  • PCIe Generation

    AMD Instinct MI250
    PCIe 4.0
    AMD Radeon RX 6500 XT
    PCIe 4.0 x4

    Which one should you pick?

    Choose AMD Instinct MI250 if you want the higher memory bus width (8192 bit vs 64 bit) and the higher memory bandwidth (3200 GB/s vs 144 GB/s).

    Choose AMD Radeon RX 6500 XT if you want the higher boost clock (2815 MHz vs 1700 MHz) and the lower TDP (107 W vs 500 W).

    Price comparison

    RetailerAMD Instinct MI250AMD Radeon RX 6500 XT
    Consumercarts listing

    $199.00

    View on Consumercarts listing

    Disclaimer: The price and specification of the given product may differ from the actual product. Please confirm on the retailer's website before buying.

    Verdict

    AMD Radeon RX 6500 XT

    5.5 / 10 Expert Rating

    A solid entry-level pick if its price and 4GB VRAM allocation match your target resolution.

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