AMD

AMD Instinct MI250

GPU Brand:: AMD
Series:: Instinct MI200 Series
Tier:: Datacenter
Board Partner:: AMD (Reference)
VRAM:: 128 GB
Memory Type:: HBM2e
TDP:: 500W

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Manufacturer: AMD Last updated: October 9, 2026

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AMD Instinct MI250 Review

AMD Instinct MI250 graphics card, 128 GB VRAM, 500W | 560W Peak TDP.

The AMD Instinct MI250 is an AMD reference-design graphics card in the Instinct MI200 Series lineup, launched 11/08/2021. It ships with 128 GB of HBM2e and runs within a 500W | 560W Peak power envelope. This entry reflects AMD's official reference specification; board-partner card variants may differ in clocks, cooling, and power delivery.

Performance and Architecture

Platform and Connectivity

The AMD Instinct MI250 follows AMD's Instinct reference design conventions for memory, display outputs, and bus interface as specified by AMD.

Comparison to Alternatives

Within this catalog's Instinct MI200 Series listings, the AMD Instinct MI250 reference specification sits alongside board-partner variants of the same chip, which may offer different clocks, cooling, and pricing.

Our verdict

Reviewed by Burooj Alam. Rated by us, not by users.

Best for

Buyers comparing AMD's official reference specifications
Researching a chip before choosing a board-partner card
Workstation/datacenter procurement research

Not for

Buyers wanting a specific retail card with cooler and warranty details
Overclocking-focused enthusiasts (reference clocks only)

Specifications

What these specs mean

Platform

GPU Brand	AMD
Board Partner	Reference

Identity and type

Product Type	Datacenter Accelerator
Series	Instinct
Tier	Datacenter

Performance

Memory Type	HBM2E
Boost Clock	1700 MHz

Physical & Power

TDP	500 W
Slot Width	Not Applicable

Silicon

Architecture	CDNA2
Process Node	TSMC 6nm FinFET
Shader Units	13312
Compute Blocks	208

Memory

VRAM Capacity	128 GB
Memory Bus Width	8192 bit
Memory Bandwidth	3200 GB/s

Host interface

PCIe Generation	PCIe 4.0
PCIe Lanes	16

Physical and cooling

Cooling Type	Passive

Market and workstation

Launch Date	11/08/2021
ECC Memory	Yes

FAQs

What are the key specifications of the AMD Instinct MI250?

Key specs for the AMD Instinct MI250: VRAM Capacity 128 GB, Memory Bandwidth 3200 GB/s, Boost Clock 1700 MHz, TDP 500 W, Form Factor OAM Module, Architecture CDNA2.

Who is the AMD Instinct MI250 best suited to?

Best suited to: Buyers comparing AMD's official reference specifications; Researching a chip before choosing a board-partner card; Workstation/datacenter procurement research.

What are the drawbacks of the AMD Instinct MI250?

Not the best fit for: Buyers wanting a specific retail card with cooler and warranty details; Overclocking-focused enthusiasts (reference clocks only).