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AMD Instinct MI250 vs AMD Radeon RX 6750 GRE 12GB: Comparison
AMD Instinct MI250 and AMD Radeon RX 6750 GRE 12GB differ on memory type: AMD Instinct MI250 at HBM2E, AMD Radeon RX 6750 GRE 12GB at GDDR6, which puts AMD Radeon RX 6750 GRE 12GB ahead on that measure. They match on gpu brand and pcie interface.
Specs
| Specification | ![]() | ![]() |
|---|---|---|
| GPU Brand | AMD | AMD |
| Series | Instinct MI200 Series | Radeon RX 6000 |
| Board Partner | AMD (Reference) | AMD Reference (China OEM/retail market card) |
| Memory Type | HBM2E | GDDR6 |
| TDP | 500W | 560W Peak | 220 W |
| Architecture | CDNA2 | RDNA 2 |
| Stream Processors | 13,312 | 2560 |
| PCIe Interface | PCIe 4.0 x16 | PCIe 4.0 x16 |
Verdict
AMD Radeon RX 6750 GRE 12GB
6.5 / 10 Expert Rating
A capable but regionally-locked RDNA 2 card; fine value if you can find one, but the RX 6700 XT and RX 6750 XT cover the same ground with wider availability.




