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AMD Instinct MI250 vs NVIDIA Quadro RTX A6000: Comparison
AMD Instinct MI250 and NVIDIA Quadro RTX A6000 separate most on memory bandwidth: AMD Instinct MI250 at 3200 GB/s, NVIDIA Quadro RTX A6000 at 768 GB/s, 76% in favour of AMD Instinct MI250.
Specs
| Specification | ![]() | ![]() |
|---|---|---|
| GPU Brand | AMD | NVIDIA |
| Series | Instinct MI200 Series | RTX Ampere Generation |
| Board Partner | AMD (Reference) | NVIDIA Reference (workstation, no AIB partners) |
| Memory Type | HBM2E | GDDR6 |
| TDP | 500W | 560W Peak | 300 W |
| Architecture | CDNA2 | Ampere |
| Memory Bandwidth | 3200 GB/s | 768 GB/s-76% |
| Launch Date | 11/08/2021 | 2020-10 |
| PCIe Interface | PCIe 4.0 x16 | PCIe 4.0 x16 |
Verdict
NVIDIA Quadro RTX A6000
7.9 / 10 Expert Rating
Still a genuinely useful 48GB workstation card on the secondhand market, even four years after launch - just expect a real gap versus current RTX PRO Blackwell cards in ray tracing and AI performance.




