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AMD Instinct MI100 vs AMD Radeon PRO W7500: Comparison
Instinct MI100 vs Radeon PRO W7500: the tdp difference
On tdp the spread is 329%, Instinct MI100 300 W against Radeon PRO W7500 70 W, so Radeon PRO W7500 takes it. Add slot width to that, 2 on the Instinct MI100 versus 1 on the Radeon PRO W7500, and the pattern holds. Memory bus width runs the same way, 4096 bit on the Instinct MI100 versus 128 bit on the Radeon PRO W7500, another win for Instinct MI100. Radeon PRO W7500 also leads on card length, 267 mm on the Instinct MI100 versus 167 mm on the Radeon PRO W7500. Add boost clock to that, 1502 MHz on the Instinct MI100 versus 2260 MHz on the Radeon PRO W7500, and the pattern holds.
Who each one is for
The Instinct MI100 suits buyers comparing AMD's official reference specifications and researching a chip before choosing a board-partner card, though it is not the pick for overclocking-focused enthusiasts (reference clocks only). It is the wrong buy for buyers wanting a specific retail card with cooler and warranty details. Buy the Radeon PRO W7500 for small-form-factor workstations needing AV1 hardware encode and basic CAD and 2D/3D content creation on a budget, though it is the wrong buy for CUDA-dependent professional 3D software and heavy rendering or simulation workloads. Our rating of the Radeon PRO W7500 (6.8/10): A strong entry-level workstation pick if AV1 encode or DisplayPort 2.1 output matter to your workflow; CUDA-dependent software users should still lean NVIDIA.
Frequently asked questions
Do the Instinct MI100 and Radeon PRO W7500 differ on board partner?
Yes. Board Partner reads Reference on the Instinct MI100 versus AMD Reference on the Radeon PRO W7500.
Is the GPU Brand the same on the Instinct MI100 and Radeon PRO W7500?
It is. Both are listed at AMD, so it is not a reason to pick one over the other.
Specs and benchmarks
GPU Brand
- AMD Instinct MI100
- AMD
- AMD Radeon PRO W7500
- AMD
Series
- AMD Instinct MI100
- Instinct
- AMD Radeon PRO W7500
- Radeon RX 7000
Board Partner
- AMD Instinct MI100
- Reference
- AMD Radeon PRO W7500
- AMD Reference
Tier
- AMD Instinct MI100
- Datacenter
- AMD Radeon PRO W7500
- Entry (Workstation)
Memory Type
- AMD Instinct MI100
- HBM2
- AMD Radeon PRO W7500
- GDDR6Best
Boost Clock
- AMD Instinct MI100
- 1502 MHz-34%
- AMD Radeon PRO W7500
- 2260 MHzBest
TDP
- AMD Instinct MI100
- 300 W-329%
- AMD Radeon PRO W7500
- 70 WBest
Architecture
- AMD Instinct MI100
- CDNA
- AMD Radeon PRO W7500
- RDNA 3
Card Length
- AMD Instinct MI100
- 267 mm-60%
- AMD Radeon PRO W7500
- 167 mmBest
Slot Width
- AMD Instinct MI100
- 2-100%
- AMD Radeon PRO W7500
- 1Best
Shader Units
- AMD Instinct MI100
- 7680
- AMD Radeon PRO W7500
- 1792
Compute Blocks
- AMD Instinct MI100
- 120
- AMD Radeon PRO W7500
- 28
Memory Bus Width
- AMD Instinct MI100
- 4096 bitBest
- AMD Radeon PRO W7500
- 128 bit-97%
PCIe Generation
- AMD Instinct MI100
- PCIe 4.0
- AMD Radeon PRO W7500
- PCIe 4.0 x8
Which one should you pick?
Choose AMD Instinct MI100 if you want the higher memory bus width (4096 bit vs 128 bit).
Choose AMD Radeon PRO W7500 if you want the higher boost clock (2260 MHz vs 1502 MHz), the lower TDP (70 W vs 300 W) and the lower card length (167 mm vs 267 mm).
Verdict
AMD Radeon PRO W7500
6.8 / 10 Expert Rating
A strong entry-level workstation pick if AV1 encode or DisplayPort 2.1 output matter to your workflow; CUDA-dependent software users should still lean NVIDIA.




