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AMD Instinct MI100 vs AMD Radeon R7 250X: Comparison
What is the difference between Instinct MI100 and Radeon R7 250X?
On tdp the spread is 216%, Instinct MI100 300 W against Radeon R7 250X 95 W, so Radeon R7 250X takes it. Memory bandwidth runs the same way, 1200 GB/s on the Instinct MI100 versus 72 GB/s on the Radeon R7 250X, another win for Instinct MI100. Instinct MI100 also leads on memory bus width, 4096 bit on the Instinct MI100 versus 128 bit on the Radeon R7 250X. Add boost clock to that, 1502 MHz on the Instinct MI100 versus 1000 MHz on the Radeon R7 250X, and the pattern holds. They differ on product type too, Datacenter Accelerator on the Instinct MI100 versus Desktop Add-In Card on the Radeon R7 250X. They differ on board partner too, Reference on the Instinct MI100 versus AMD on the Radeon R7 250X. They differ on architecture too, CDNA on the Instinct MI100 versus GCN on the Radeon R7 250X.
Who each one is for
The Instinct MI100 is the one to take for buyers comparing AMD's official reference specifications and researching a chip before choosing a board-partner card, though it is not the pick for overclocking-focused enthusiasts (reference clocks only). It is the wrong buy for buyers wanting a specific retail card with cooler and warranty details. The Radeon R7 250X suits buyers comparing AMD's official reference specifications and researching a chip before choosing a board-partner card, though it is the wrong buy for overclocking-focused enthusiasts (reference clocks only). Avoid it for buyers wanting a specific retail card with cooler and warranty details.
Frequently asked questions
Do the Instinct MI100 and Radeon R7 250X differ on vram capacity?
Yes. VRAM Capacity reads 32 GB on the Instinct MI100 versus 1 GB on the Radeon R7 250X.
Is the GPU Brand the same on the Instinct MI100 and Radeon R7 250X?
It is. Both are listed at AMD, so it is not a reason to pick one over the other.
Specs and benchmarks
GPU Brand
- AMD Instinct MI100
- AMD
- AMD Radeon R7 250X
- AMD
Product Type
- AMD Instinct MI100
- Datacenter Accelerator
- AMD Radeon R7 250X
- Desktop Add-In Card
Series
- AMD Instinct MI100
- Instinct
- AMD Radeon R7 250X
- Radeon R7 200 Series
Board Partner
- AMD Instinct MI100
- Reference
- AMD Radeon R7 250X
- AMD (Reference)
Memory Type
- AMD Instinct MI100
- HBM2
- AMD Radeon R7 250X
- GDDR5Best
Boost Clock
- AMD Instinct MI100
- 1502 MHzBest
- AMD Radeon R7 250X
- 1000 MHz-33%
TDP
- AMD Instinct MI100
- 300 W-216%
- AMD Radeon R7 250X
- 95 WBest
Architecture
- AMD Instinct MI100
- CDNA
- AMD Radeon R7 250X
- GCN
Process Node
- AMD Instinct MI100
- TSMC 7nm FinFET
- AMD Radeon R7 250X
- Other
Slot Width
- AMD Instinct MI100
- 2
- AMD Radeon R7 250X
- 2
Shader Units
- AMD Instinct MI100
- 7680
- AMD Radeon R7 250X
- 640
VRAM Capacity
- AMD Instinct MI100
- 32 GBBest
- AMD Radeon R7 250X
- 1 GB
Memory Bus Width
- AMD Instinct MI100
- 4096 bitBest
- AMD Radeon R7 250X
- 128 bit-97%
Memory Bandwidth
- AMD Instinct MI100
- 1200 GB/sBest
- AMD Radeon R7 250X
- 72 GB/s-94%
Launch Date
- AMD Instinct MI100
- 11/16/2020
- AMD Radeon R7 250X
- February 2014
Form Factor
- AMD Instinct MI100
- PCIe Add-in Card
- AMD Radeon R7 250X
- Component
Which one should you pick?
Choose AMD Instinct MI100 if you want the higher boost clock (1502 MHz vs 1000 MHz), the lower slot width (2 vs 2) and the higher memory bus width (4096 bit vs 128 bit).
Choose AMD Radeon R7 250X if you want the lower TDP (95 W vs 300 W).




