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AMD Instinct MI100 vs AMD Radeon R9 M275X: Comparison
What is the difference between Instinct MI100 and Radeon R9 M275X?
The gap that matters here is memory bandwidth: Instinct MI100 1200 GB/s against Radeon R9 M275X 72 GB/s, which puts Instinct MI100 94% ahead. Instinct MI100 also leads on boost clock, 1502 MHz on the Instinct MI100 versus 925 MHz on the Radeon R9 M275X. Instinct MI100 also leads on memory bus width, 4096 bit on the Instinct MI100 versus 128 bit on the Radeon R9 M275X. There is a split on product type as well, Datacenter Accelerator on the Instinct MI100 versus Laptop GPU on the Radeon R9 M275X. Board partner is not the same on both, Reference on the Instinct MI100 versus AMD on the Radeon R9 M275X. There is a split on architecture as well, CDNA on the Instinct MI100 versus GCN on the Radeon R9 M275X. They differ on shader units too, 7680 on the Instinct MI100 versus 640 on the Radeon R9 M275X.
Which should you buy, Instinct MI100 or Radeon R9 M275X?
Buy the Instinct MI100 for buyers comparing AMD's official reference specifications and researching a chip before choosing a board-partner card, though it is not the pick for overclocking-focused enthusiasts (reference clocks only). It is the wrong buy for buyers wanting a specific retail card with cooler and warranty details. The Radeon R9 M275X is the one to take for buyers comparing AMD's official reference specifications and researching a chip before choosing a board-partner card, though it is the wrong buy for overclocking-focused enthusiasts (reference clocks only). Avoid it for buyers wanting a specific retail card with cooler and warranty details.
Frequently asked questions
Do the Instinct MI100 and Radeon R9 M275X differ on vram capacity?
Yes. VRAM Capacity reads 32 GB on the Instinct MI100 versus 4 GB on the Radeon R9 M275X.
Is the GPU Brand the same on the Instinct MI100 and Radeon R9 M275X?
It is. Both are listed at AMD, so it is not a reason to pick one over the other.
Specs and benchmarks
GPU Brand
- AMD Instinct MI100
- AMD
- AMD Radeon R9 M275X
- AMD
Product Type
- AMD Instinct MI100
- Datacenter Accelerator
- AMD Radeon R9 M275X
- Laptop GPU
Series
- AMD Instinct MI100
- Instinct
- AMD Radeon R9 M275X
- Radeon R9 200 Series
Board Partner
- AMD Instinct MI100
- Reference
- AMD Radeon R9 M275X
- AMD (Reference)
Memory Type
- AMD Instinct MI100
- HBM2
- AMD Radeon R9 M275X
- GDDR5Best
Boost Clock
- AMD Instinct MI100
- 1502 MHzBest
- AMD Radeon R9 M275X
- 925 MHz-38%
Architecture
- AMD Instinct MI100
- CDNA
- AMD Radeon R9 M275X
- GCN
Process Node
- AMD Instinct MI100
- TSMC 7nm FinFET
- AMD Radeon R9 M275X
- Other
Shader Units
- AMD Instinct MI100
- 7680
- AMD Radeon R9 M275X
- 640
Compute Blocks
- AMD Instinct MI100
- 120
- AMD Radeon R9 M275X
- 10
VRAM Capacity
- AMD Instinct MI100
- 32 GBBest
- AMD Radeon R9 M275X
- 4 GB
Memory Bus Width
- AMD Instinct MI100
- 4096 bitBest
- AMD Radeon R9 M275X
- 128 bit-97%
Memory Bandwidth
- AMD Instinct MI100
- 1200 GB/sBest
- AMD Radeon R9 M275X
- 72 GB/s-94%
Launch Date
- AMD Instinct MI100
- 11/16/2020
- AMD Radeon R9 M275X
- January 2014
Form Factor
- AMD Instinct MI100
- PCIe Add-in Card
- AMD Radeon R9 M275X
- Component
Which one should you pick?
Choose AMD Instinct MI100 if you want the higher boost clock (1502 MHz vs 925 MHz), the higher memory bus width (4096 bit vs 128 bit) and the higher memory bandwidth (1200 GB/s vs 72 GB/s).
Choose AMD Radeon R9 M275X if you already have it on hand or find it at a lower price.




