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AMD Instinct MI100 vs NVIDIA GeForce RTX 4060 Ti 16GB: Comparison
What is the difference between AMD Instinct MI100 and NVIDIA GeForce RTX 4060 Ti 16GB?
The gap that matters here is tdp: AMD Instinct MI100 300 W against NVIDIA GeForce RTX 4060 Ti 16GB 165 W, which puts NVIDIA GeForce RTX 4060 Ti 16GB 82% ahead. Add boost clock to that, 1502 MHz on the AMD Instinct MI100 versus 2535 MHz on the NVIDIA GeForce RTX 4060 Ti 16GB, and the pattern holds. Add memory bus width to that, 4096 bit on the AMD Instinct MI100 versus 128 bit on the NVIDIA GeForce RTX 4060 Ti 16GB, and the pattern holds. Architecture is not the same on both, CDNA on the AMD Instinct MI100 versus Ada Lovelace on the NVIDIA GeForce RTX 4060 Ti 16GB. They differ on shader units too, 7680 on the AMD Instinct MI100 versus 4352 on the NVIDIA GeForce RTX 4060 Ti 16GB.
AMD Instinct MI100 vs NVIDIA GeForce RTX 4060 Ti 16GB: which one fits your build
The AMD Instinct MI100 suits buyers comparing AMD's official reference specifications and researching a chip before choosing a board-partner card, though it is not the pick for overclocking-focused enthusiasts (reference clocks only). It is the wrong buy for buyers wanting a specific retail card with cooler and warranty details. it is the wrong buy for buyers on a strict budget who only game at 1080p. The same goes for 1440p gaming and light local AI workloads where 8GB feels tight. Our rating of the NVIDIA GeForce RTX 4060 Ti 16GB (7.5/10): the same AD106 core as the 8GB card with double the memory, which matters most for modded games and light local AI work.
Frequently asked questions
Do the AMD Instinct MI100 and NVIDIA GeForce RTX 4060 Ti 16GB differ on gpu brand?
Yes. GPU Brand reads AMD on the AMD Instinct MI100 versus NVIDIA on the NVIDIA GeForce RTX 4060 Ti 16GB.
Specs and benchmarks
GPU Brand
- AMD Instinct MI100
- AMD
- NVIDIA GeForce RTX 4060 Ti 16GB
- NVIDIA
Tier
- AMD Instinct MI100
- Datacenter
- NVIDIA GeForce RTX 4060 Ti 16GB
- Mainstream
Memory Type
- AMD Instinct MI100
- HBM2
- NVIDIA GeForce RTX 4060 Ti 16GB
- GDDR6Best
Boost Clock
- AMD Instinct MI100
- 1502 MHz-41%
- NVIDIA GeForce RTX 4060 Ti 16GB
- 2535 MHzBest
TDP
- AMD Instinct MI100
- 300 W-82%
- NVIDIA GeForce RTX 4060 Ti 16GB
- 165 WBest
Architecture
- AMD Instinct MI100
- CDNA
- NVIDIA GeForce RTX 4060 Ti 16GB
- Ada Lovelace (AD106)
Shader Units
- AMD Instinct MI100
- 7680
- NVIDIA GeForce RTX 4060 Ti 16GB
- 4352
Memory Bus Width
- AMD Instinct MI100
- 4096 bitBest
- NVIDIA GeForce RTX 4060 Ti 16GB
- 128 bit-97%
Which one should you pick?
Choose AMD Instinct MI100 if you want the higher memory bus width (4096 bit vs 128 bit).
Choose NVIDIA GeForce RTX 4060 Ti 16GB if you want the higher boost clock (2535 MHz vs 1502 MHz) and the lower TDP (165 W vs 300 W).
Price comparison
| Retailer | AMD Instinct MI100 | NVIDIA GeForce RTX 4060 Ti 16GB |
|---|---|---|
| Consumercarts listing | $499.00 View on Consumercarts listing |
Disclaimer: The price and specification of the given product may differ from the actual product. Please confirm on the retailer's website before buying.
Verdict
NVIDIA GeForce RTX 4060 Ti 16GB
7.5 / 10 Expert Rating
The same AD106 core as the 8GB card with double the memory, which matters most for modded games and light local AI work.




