AMD Instinct MI350X
- GPU Brand:
- AMD
- Series:
- Instinct MI350 Series
- Tier:
- Datacenter
- Board Partner:
- AMD (Reference)
- VRAM:
- 288 GB
- Memory Type:
- HBM3E
- TDP:
- 1000W (TBP)
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Manufacturer: AMD Last updated: October 9, 2026
AMD Instinct MI350X Review
AMD Instinct MI350X graphics card, 288 GB VRAM, 1000W (TBP) TDP.
The AMD Instinct MI350X is an AMD reference-design graphics card in the Instinct MI350 Series lineup, launched 6/12/2025. It ships with 288 GB of HBM3E and runs within a 1000W (TBP) power envelope. This entry reflects AMD's official reference specification; board-partner card variants may differ in clocks, cooling, and power delivery.
Performance and Architecture
The AMD Instinct MI350X is an AMD reference-design graphics card in the Instinct MI350 Series lineup, launched 6/12/2025. It ships with 288 GB of HBM3E and runs within a 1000W (TBP) power envelope. This entry reflects AMD's official reference specification; board-partner card variants may differ in clocks, cooling, and power delivery.
Platform and Connectivity
The AMD Instinct MI350X follows AMD's Instinct reference design conventions for memory, display outputs, and bus interface as specified by AMD.
Comparison to Alternatives
Within this catalog's Instinct MI350 Series listings, the AMD Instinct MI350X reference specification sits alongside board-partner variants of the same chip, which may offer different clocks, cooling, and pricing.
Our verdict
Reviewed by Burooj Alam. Rated by us, not by users.
Best for
- Buyers comparing AMD's official reference specifications
- Researching a chip before choosing a board-partner card
- Workstation/datacenter procurement research
Not for
- Buyers wanting a specific retail card with cooler and warranty details
- Overclocking-focused enthusiasts (reference clocks only)
Specifications
What these specs meanPlatform
| GPU Brand | AMD |
|---|---|
| Board Partner | Reference |
Identity and type
| Product Type | Datacenter Accelerator |
|---|---|
| Series | Instinct |
| Tier | Datacenter |
Performance
| Memory Type | HBM3E |
|---|---|
| Boost Clock | 2200 MHz |
Silicon
| Architecture | CDNA 4 |
|---|---|
| Process Node | TSMC 3nm | 6nm FinFET |
| Shader Units | 16384 |
| Compute Blocks | 256 |
Ray tracing and AI
| AI Accelerators | 1024 |
|---|
Memory
| VRAM Capacity | 288 GB |
|---|---|
| Memory Bus Width | 8192 bit |
| Memory Bandwidth | 8000 GB/s |
| Cache Size | 256 MB |
Power
| Board Power | 1000 W |
|---|
Host interface
| PCIe Generation | PCIe 5.0 |
|---|---|
| PCIe Lanes | 16 |
Physical and cooling
| Cooling Type | Passive |
|---|
Market and workstation
| Launch Date | 6/12/2025 |
|---|---|
| ECC Memory | Yes |
FAQs
What are the key specifications of the AMD Instinct MI350X?
Key specs for the AMD Instinct MI350X: VRAM Capacity 288 GB, Memory Bandwidth 8000 GB/s, Boost Clock 2200 MHz, Form Factor OAM Module, Architecture CDNA 4, Lithography TSMC 3nm | 6nm FinFET.
Who is the AMD Instinct MI350X best suited to?
Best suited to: Buyers comparing AMD's official reference specifications; Researching a chip before choosing a board-partner card; Workstation/datacenter procurement research.
What are the drawbacks of the AMD Instinct MI350X?
Not the best fit for: Buyers wanting a specific retail card with cooler and warranty details; Overclocking-focused enthusiasts (reference clocks only).