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AMD Instinct MI210 vs AMD Radeon R9 M275X: Comparison
Instinct MI210 vs Radeon R9 M275X memory bandwidth compared
The gap that matters here is memory bandwidth: Instinct MI210 1600 GB/s against Radeon R9 M275X 72 GB/s, which puts Instinct MI210 96% ahead. Add boost clock to that, 1700 MHz on the Instinct MI210 versus 925 MHz on the Radeon R9 M275X, and the pattern holds. Add memory bus width to that, 4096 bit on the Instinct MI210 versus 128 bit on the Radeon R9 M275X, and the pattern holds. They differ on compute blocks too, 104 on the Instinct MI210 versus 10 on the Radeon R9 M275X.
Which should you buy, Instinct MI210 or Radeon R9 M275X?
The Instinct MI210 is the one to take for double-precision workloads that don't need MI250X-level throughput, though it is not built for any desktop or workstation build - compute-only, no display output and maximum-throughput HPC nodes (use MI250X instead). It is equally the pick for HPC and AI deployments in standard PCIe-slot servers without OAM sled support. The Radeon R9 M275X suits buyers comparing AMD's official reference specifications and researching a chip before choosing a board-partner card, though it is not the pick for overclocking-focused enthusiasts (reference clocks only). It is not the one for buyers wanting a specific retail card with cooler and warranty details. Our rating of the Instinct MI210 (7.3/10): A practical, PCIe-slot-friendly way to get CDNA 2 compute into a standard server, useful for smaller HPC and AI deployments, but clearly the entry point of its generation next to the dual-die MI250X and now well behind the MI300 series.
Frequently asked questions
Do the Instinct MI210 and Radeon R9 M275X differ on board partner?
Yes. Board Partner reads AMD Reference on the Instinct MI210 versus AMD on the Radeon R9 M275X.
Is the GPU Brand the same on the Instinct MI210 and Radeon R9 M275X?
It is. Both are listed at AMD, so it is not a reason to pick one over the other.
Specs and benchmarks
GPU Brand
- AMD Instinct MI210
- AMD
- AMD Radeon R9 M275X
- AMD
Series
- AMD Instinct MI210
- Instinct MI200
- AMD Radeon R9 M275X
- Radeon R9 200 Series
Board Partner
- AMD Instinct MI210
- AMD Reference (PCIe dual-slot card, data center/OEM only)
- AMD Radeon R9 M275X
- AMD (Reference)
Memory Type
- AMD Instinct MI210
- HBM2E
- AMD Radeon R9 M275X
- GDDR5Best
Boost Clock
- AMD Instinct MI210
- 1700 MHzBest
- AMD Radeon R9 M275X
- 925 MHz-46%
Architecture
- AMD Instinct MI210
- CDNA 2 (single Graphics Compute Die)
- AMD Radeon R9 M275X
- GCN
Process Node
- AMD Instinct MI210
- TSMC 6nm
- AMD Radeon R9 M275X
- Other
Compute Blocks
- AMD Instinct MI210
- 104
- AMD Radeon R9 M275X
- 10
Memory Bus Width
- AMD Instinct MI210
- 4096 bitBest
- AMD Radeon R9 M275X
- 128 bit-97%
Memory Bandwidth
- AMD Instinct MI210
- 1600 GB/sBest
- AMD Radeon R9 M275X
- 72 GB/s-95%
Launch Date
- AMD Instinct MI210
- 2022-03
- AMD Radeon R9 M275X
- January 2014
Which one should you pick?
Choose AMD Instinct MI210 if you want the higher boost clock (1700 MHz vs 925 MHz), the higher memory bus width (4096 bit vs 128 bit) and the higher memory bandwidth (1600 GB/s vs 72 GB/s).
Choose AMD Radeon R9 M275X if you already have it on hand or find it at a lower price.
Verdict
AMD Instinct MI210
7.3 / 10 Expert Rating
A practical, PCIe-slot-friendly way to get CDNA 2 compute into a standard server, useful for smaller HPC and AI deployments, but clearly the entry point of its generation next to the dual-die MI250X and now well behind the MI300 series.