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AMD Instinct MI210 vs AMD FirePro S7100X: Comparison
Instinct MI210 vs FirePro S7100X: the tdp difference
Start with tdp, because it is the widest measured gap between them: Instinct MI210 300 W against FirePro S7100X 100 W, 200% in favour of FirePro S7100X. Instinct MI210 also leads on memory bandwidth, 1600 GB/s on the Instinct MI210 versus 160 GB/s on the FirePro S7100X. Instinct MI210 also leads on memory bus width, 4096 bit on the Instinct MI210 versus 256 bit on the FirePro S7100X. Pcie generation is not the same on both, PCIe 4.0 x16 on the Instinct MI210 versus PCIe 3.0 on the FirePro S7100X.
Who each one is for
Buy the Instinct MI210 for double-precision workloads that don't need MI250X-level throughput, though it is the wrong buy for any desktop or workstation build - compute-only, no display output and maximum-throughput HPC nodes (use MI250X instead). It also earns its place with HPC and AI deployments in standard PCIe-slot servers without OAM sled support. The FirePro S7100X suits buyers comparing AMD's official reference specifications and researching a chip before choosing a board-partner card, though it is not the pick for overclocking-focused enthusiasts (reference clocks only). Avoid it for buyers wanting a specific retail card with cooler and warranty details. Our rating of the Instinct MI210 (7.3/10): A practical, PCIe-slot-friendly way to get CDNA 2 compute into a standard server, useful for smaller HPC and AI deployments, but clearly the entry point of its generation next to the dual-die MI250X and now well behind the MI300 series.
Frequently asked questions
Do the Instinct MI210 and FirePro S7100X differ on board partner?
Yes. Board Partner reads AMD Reference on the Instinct MI210 versus Reference on the FirePro S7100X.
Is the GPU Brand the same on the Instinct MI210 and FirePro S7100X?
It is. Both are listed at AMD, so it is not a reason to pick one over the other.
Specs and benchmarks
GPU Brand
- AMD Instinct MI210
- AMD
- AMD FirePro S7100X
- AMD
Series
- AMD Instinct MI210
- Instinct MI200
- AMD FirePro S7100X
- Legacy
Board Partner
- AMD Instinct MI210
- AMD Reference (PCIe dual-slot card, data center/OEM only)
- AMD FirePro S7100X
- Reference
Tier
- AMD Instinct MI210
- Datacenter / AI Accelerator
- AMD FirePro S7100X
- Workstation
Memory Type
- AMD Instinct MI210
- HBM2E
- AMD FirePro S7100X
- GDDR5Best
TDP
- AMD Instinct MI210
- 300 W-200%
- AMD FirePro S7100X
- 100 WBest
Architecture
- AMD Instinct MI210
- CDNA 2 (single Graphics Compute Die)
- AMD FirePro S7100X
- GCN
Process Node
- AMD Instinct MI210
- TSMC 6nm
- AMD FirePro S7100X
- Other
Compute Blocks
- AMD Instinct MI210
- 104
- AMD FirePro S7100X
- 32
Memory Bus Width
- AMD Instinct MI210
- 4096 bitBest
- AMD FirePro S7100X
- 256 bit-94%
Memory Bandwidth
- AMD Instinct MI210
- 1600 GB/sBest
- AMD FirePro S7100X
- 160 GB/s-90%
PCIe Generation
- AMD Instinct MI210
- PCIe 4.0 x16
- AMD FirePro S7100X
- PCIe 3.0
Launch Date
- AMD Instinct MI210
- 2022-03
- AMD FirePro S7100X
- May 2016
Which one should you pick?
Choose AMD Instinct MI210 if you want the higher memory bus width (4096 bit vs 256 bit) and the higher memory bandwidth (1600 GB/s vs 160 GB/s).
Choose AMD FirePro S7100X if you want the lower TDP (100 W vs 300 W).
Verdict
AMD Instinct MI210
7.3 / 10 Expert Rating
A practical, PCIe-slot-friendly way to get CDNA 2 compute into a standard server, useful for smaller HPC and AI deployments, but clearly the entry point of its generation next to the dual-die MI250X and now well behind the MI300 series.




