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AMD Instinct MI210 vs NVIDIA CMP 50HX: Comparison
What is the difference between AMD Instinct MI210 and NVIDIA CMP 50HX?
The gap that matters here is vram: AMD Instinct MI210 64 GB against NVIDIA CMP 50HX 8 GB, which puts AMD Instinct MI210 88% ahead. Memory bandwidth runs the same way, 1600 GB/s on the AMD Instinct MI210 versus 448 GB/s on the NVIDIA CMP 50HX, another win for AMD Instinct MI210. Memory bus width runs the same way, 4096 bit on the AMD Instinct MI210 versus 256 bit on the NVIDIA CMP 50HX, another win for AMD Instinct MI210. NVIDIA CMP 50HX also leads on tdp, 300 W on the AMD Instinct MI210 versus 225 W on the NVIDIA CMP 50HX.
AMD Instinct MI210 vs NVIDIA CMP 50HX: which one fits your build
The AMD Instinct MI210 is the one to take for double-precision workloads that don't need MI250X-level throughput, though it is not built for any desktop or workstation build - compute-only, no display output and maximum-throughput HPC nodes (use MI250X instead). It is equally the pick for HPC and AI deployments in standard PCIe-slot servers without OAM sled support. The NVIDIA CMP 50HX suits secondary-market buyers mining non-Ethereum proof-of-work coins and repurposing as a cheap compute card for non-graphics CUDA workloads. It is not the one for gaming, no display output at all, cannot drive a monitor under any configuration. Our rating of the AMD Instinct MI210 (7.3/10): A practical, PCIe-slot-friendly way to get CDNA 2 compute into a standard server, useful for smaller HPC and AI deployments, but clearly the entry point of its generation next to the dual-die MI250X and now well behind the MI300 series.
Frequently asked questions
Do the AMD Instinct MI210 and NVIDIA CMP 50HX differ on boost clock?
Yes. Boost Clock reads 1700 MHz on the AMD Instinct MI210 versus 1665 MHz on the NVIDIA CMP 50HX.
Is the Card Length the same on the AMD Instinct MI210 and NVIDIA CMP 50HX?
It is. Both are listed at 267 mm, so it is not a reason to pick one over the other.
Specs and benchmarks
GPU Brand
- AMD Instinct MI210
- AMD
- NVIDIA CMP 50HX
- NVIDIA
Series
- AMD Instinct MI210
- Instinct MI200
- NVIDIA CMP 50HX
- CMP (Cryptocurrency Mining Processor)
Board Partner
- AMD Instinct MI210
- AMD Reference (PCIe dual-slot card, data center/OEM only)
- NVIDIA CMP 50HX
- ASUS, Colorful, Gigabyte, Inno3D, MSI, Palit, Zotac (reference blower design)
VRAM
- AMD Instinct MI210
- 64 GBBest
- NVIDIA CMP 50HX
- 8 GB-87%
Tier
- AMD Instinct MI210
- Datacenter / AI Accelerator
- NVIDIA CMP 50HX
- Mid-Level Mining (2021)
Memory Type
- AMD Instinct MI210
- HBM2E
- NVIDIA CMP 50HX
- GDDR6Best
Boost Clock
- AMD Instinct MI210
- 1700 MHzBest
- NVIDIA CMP 50HX
- 1665 MHz-2%
TDP
- AMD Instinct MI210
- 300 W-33%
- NVIDIA CMP 50HX
- 225 WBest
Architecture
- AMD Instinct MI210
- CDNA 2 (single Graphics Compute Die)
- NVIDIA CMP 50HX
- Ampere (GA104), the first Ampere-based tier of the CMP lineup
Process Node
- AMD Instinct MI210
- TSMC 6nm
- NVIDIA CMP 50HX
- Samsung 8nm (8N)
Card Length
- AMD Instinct MI210
- 267 mm
- NVIDIA CMP 50HX
- 267 mm
Slot Width
- AMD Instinct MI210
- 2
- NVIDIA CMP 50HX
- 2
Memory Bus Width
- AMD Instinct MI210
- 4096 bitBest
- NVIDIA CMP 50HX
- 256 bit-94%
Memory Bandwidth
- AMD Instinct MI210
- 1600 GB/sBest
- NVIDIA CMP 50HX
- 448 GB/s-72%
PCIe Generation
- AMD Instinct MI210
- PCIe 4.0 x16
- NVIDIA CMP 50HX
- PCIe 4.0 x4 (deliberately narrow lane count; mining needs almost no host bandwidth)
Launch Date
- AMD Instinct MI210
- 2022-03
- NVIDIA CMP 50HX
- 2021-03
Display Outputs
- AMD Instinct MI210
- N/A - compute-only, no display output
- NVIDIA CMP 50HX
- None, no video output ports of any kind
Which one should you pick?
Choose AMD Instinct MI210 if you want the higher VRAM (64 GB vs 8 GB), the higher boost clock (1700 MHz vs 1665 MHz) and the lower card length (267 mm vs 267 mm).
Choose NVIDIA CMP 50HX if you want the lower TDP (225 W vs 300 W).
Verdict
AMD Instinct MI210
7.3 / 10 Expert Rating
A practical, PCIe-slot-friendly way to get CDNA 2 compute into a standard server, useful for smaller HPC and AI deployments, but clearly the entry point of its generation next to the dual-die MI250X and now well behind the MI300 series.
NVIDIA CMP 50HX
3.5 / 10 Expert Rating
Capable Ampere-generation mining silicon in its day, now a niche secondary-market product with no display output and diminished relevance after Ethereum's Merge.




