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AMD Instinct MI210 vs NVIDIA GeForce RTX 4080 Super: Comparison

AMD Instinct MI210 vs NVIDIA GeForce RTX 4080 Super vram compared

Vram is where these two genuinely part company, AMD Instinct MI210 64 GB against NVIDIA GeForce RTX 4080 Super 16 GB, a 75% lead for AMD Instinct MI210. AMD Instinct MI210 also leads on memory bandwidth, 1600 GB/s on the AMD Instinct MI210 versus 736 GB/s on the NVIDIA GeForce RTX 4080 Super. Memory bus width runs the same way, 4096 bit on the AMD Instinct MI210 versus 256 bit on the NVIDIA GeForce RTX 4080 Super, another win for AMD Instinct MI210. Add boost clock to that, 1700 MHz on the AMD Instinct MI210 versus 2550 MHz on the NVIDIA GeForce RTX 4080 Super, and the pattern holds.

Which should you buy, AMD Instinct MI210 or NVIDIA GeForce RTX 4080 Super?

The AMD Instinct MI210 suits double-precision workloads that don't need MI250X-level throughput, though it is the wrong buy for any desktop or workstation build - compute-only, no display output and maximum-throughput HPC nodes (use MI250X instead). It is equally the pick for HPC and AI deployments in standard PCIe-slot servers without OAM sled support. The NVIDIA GeForce RTX 4080 Super is the one to take for enthusiasts who want near-flagship 4K performance without RTX 4090 pricing, though it is not the pick for buyers chasing the absolute highest benchmark numbers regardless of cost. Our rating of the AMD Instinct MI210 (7.3/10): A practical, PCIe-slot-friendly way to get CDNA 2 compute into a standard server, useful for smaller HPC and AI deployments, but clearly the entry point of its generation next to the dual-die MI250X and now well behind the MI300 series.

Frequently asked questions

Do the AMD Instinct MI210 and NVIDIA GeForce RTX 4080 Super differ on tdp?

Yes. TDP reads 300 W on the AMD Instinct MI210 versus 320 W on the NVIDIA GeForce RTX 4080 Super.

Specs and benchmarks

  • GPU Brand

    AMD Instinct MI210
    AMD
    NVIDIA GeForce RTX 4080 Super
    NVIDIA
  • VRAM

    AMD Instinct MI210
    64 GBBest
    NVIDIA GeForce RTX 4080 Super
    16 GB-75%
  • Tier

    AMD Instinct MI210
    Datacenter / AI Accelerator
    NVIDIA GeForce RTX 4080 Super
    High End
  • Memory Type

    AMD Instinct MI210
    HBM2E
    NVIDIA GeForce RTX 4080 Super
    GDDR6XBest
  • Boost Clock

    AMD Instinct MI210
    1700 MHz-33%
    NVIDIA GeForce RTX 4080 Super
    2550 MHzBest
  • Ray Tracing Support

    AMD Instinct MI210
    No
    NVIDIA GeForce RTX 4080 Super
    Yes
  • TDP

    AMD Instinct MI210
    300 WBest
    NVIDIA GeForce RTX 4080 Super
    320 W-7%
  • Architecture

    AMD Instinct MI210
    CDNA 2 (single Graphics Compute Die)
    NVIDIA GeForce RTX 4080 Super
    Ada Lovelace (AD103)
  • Memory Bus Width

    AMD Instinct MI210
    4096 bitBest
    NVIDIA GeForce RTX 4080 Super
    256 bit-94%
  • Memory Bandwidth

    AMD Instinct MI210
    1600 GB/sBest
    NVIDIA GeForce RTX 4080 Super
    736 GB/s-54%

    Which one should you pick?

    Choose AMD Instinct MI210 if you want the higher VRAM (64 GB vs 16 GB), the lower TDP (300 W vs 320 W) and the higher memory bus width (4096 bit vs 256 bit).

    Choose NVIDIA GeForce RTX 4080 Super if you want the higher boost clock (2550 MHz vs 1700 MHz).

    Price comparison

    RetailerAMD Instinct MI210NVIDIA GeForce RTX 4080 Super
    Consumercarts listing

    $999.00

    View on Consumercarts listing

    Disclaimer: The price and specification of the given product may differ from the actual product. Please confirm on the retailer's website before buying.

    Verdict

    AMD Instinct MI210

    7.3 / 10 Expert Rating

    A practical, PCIe-slot-friendly way to get CDNA 2 compute into a standard server, useful for smaller HPC and AI deployments, but clearly the entry point of its generation next to the dual-die MI250X and now well behind the MI300 series.

    NVIDIA GeForce RTX 4080 Super

    8.5 / 10 Expert Rating

    Near-flagship 4K performance at a $200 price correction over the card it replaced.

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