Consumercarts is reader-supported. Learn more
AMD Instinct MI250 vs AMD Radeon PRO W7400: Comparison
What is the difference between Instinct MI250 and Radeon PRO W7400?
Tdp is where these two genuinely part company, Instinct MI250 500 W against Radeon PRO W7400 55 W, a 809% lead for Radeon PRO W7400. Memory bandwidth runs the same way, 3200 GB/s on the Instinct MI250 versus 172.8 GB/s on the Radeon PRO W7400, another win for Instinct MI250. Add memory bus width to that, 8192 bit on the Instinct MI250 versus 128 bit on the Radeon PRO W7400, and the pattern holds. They differ on shader units too, 13312 on the Instinct MI250 versus 1792 on the Radeon PRO W7400. Compute blocks is not the same on both, 208 on the Instinct MI250 versus 28 on the Radeon PRO W7400. Pcie generation is not the same on both, PCIe 4.0 on the Instinct MI250 versus PCIe 4.0 x8 on the Radeon PRO W7400.
Who each one is for
The Instinct MI250 is the one to take for buyers comparing AMD's official reference specifications and researching a chip before choosing a board-partner card, though it is not built for overclocking-focused enthusiasts (reference clocks only). It is not the one for buyers wanting a specific retail card with cooler and warranty details. Buy the Radeon PRO W7400 for buyers comparing AMD's official reference specifications and researching a chip before choosing a board-partner card, though it is the wrong buy for overclocking-focused enthusiasts (reference clocks only). Avoid it for buyers wanting a specific retail card with cooler and warranty details.
Frequently asked questions
Do the Instinct MI250 and Radeon PRO W7400 differ on board partner?
Yes. Board Partner reads Reference on the Instinct MI250 versus AMD on the Radeon PRO W7400.
Is the GPU Brand the same on the Instinct MI250 and Radeon PRO W7400?
It is. Both are listed at AMD, so it is not a reason to pick one over the other.
Specs and benchmarks
GPU Brand
- AMD Instinct MI250
- AMD
- AMD Radeon PRO W7400
- AMD
Series
- AMD Instinct MI250
- Instinct
- AMD Radeon PRO W7400
- Radeon PRO W7000 Series
Board Partner
- AMD Instinct MI250
- Reference
- AMD Radeon PRO W7400
- AMD (Reference)
Memory Type
- AMD Instinct MI250
- HBM2E
- AMD Radeon PRO W7400
- GDDR6Best
TDP
- AMD Instinct MI250
- 500 W-809%
- AMD Radeon PRO W7400
- 55 WBest
Architecture
- AMD Instinct MI250
- CDNA2
- AMD Radeon PRO W7400
- AMD RDNA 3
Shader Units
- AMD Instinct MI250
- 13312
- AMD Radeon PRO W7400
- 1792
Compute Blocks
- AMD Instinct MI250
- 208
- AMD Radeon PRO W7400
- 28
Memory Bus Width
- AMD Instinct MI250
- 8192 bitBest
- AMD Radeon PRO W7400
- 128 bit-98%
Memory Bandwidth
- AMD Instinct MI250
- 3200 GB/sBest
- AMD Radeon PRO W7400
- 172.8 GB/s-95%
PCIe Generation
- AMD Instinct MI250
- PCIe 4.0
- AMD Radeon PRO W7400
- PCIe 4.0 x8
Cooling Type
- AMD Instinct MI250
- Passive
- AMD Radeon PRO W7400
- Active
ECC Memory
- AMD Instinct MI250
- Yes
- AMD Radeon PRO W7400
- No
Form Factor
- AMD Instinct MI250
- OAM Module
- AMD Radeon PRO W7400
- Workstations
Which one should you pick?
Choose AMD Instinct MI250 if you want the higher memory bus width (8192 bit vs 128 bit) and the higher memory bandwidth (3200 GB/s vs 172.8 GB/s).
Choose AMD Radeon PRO W7400 if you want the lower TDP (55 W vs 500 W).




