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AMD Instinct MI250 vs AMD Radeon PRO W7500: Comparison
Instinct MI250 vs Radeon PRO W7500 tdp compared
On tdp the spread is 614%, Instinct MI250 500 W against Radeon PRO W7500 70 W, so Radeon PRO W7500 takes it. Memory bus width runs the same way, 8192 bit on the Instinct MI250 versus 128 bit on the Radeon PRO W7500, another win for Instinct MI250. Radeon PRO W7500 also leads on boost clock, 1700 MHz on the Instinct MI250 versus 2260 MHz on the Radeon PRO W7500. Architecture is not the same on both, CDNA2 on the Instinct MI250 versus RDNA 3 on the Radeon PRO W7500. They differ on slot width too, Not Applicable on the Instinct MI250 versus 1 on the Radeon PRO W7500. There is a split on shader units as well, 13312 on the Instinct MI250 versus 1792 on the Radeon PRO W7500.
Which should you buy, Instinct MI250 or Radeon PRO W7500?
The Instinct MI250 suits buyers comparing AMD's official reference specifications and researching a chip before choosing a board-partner card, though it is not built for overclocking-focused enthusiasts (reference clocks only). It is not the one for buyers wanting a specific retail card with cooler and warranty details. Buy the Radeon PRO W7500 for small-form-factor workstations needing AV1 hardware encode and basic CAD and 2D/3D content creation on a budget, though it is not the pick for CUDA-dependent professional 3D software and heavy rendering or simulation workloads. Our rating of the Radeon PRO W7500 (6.8/10): A strong entry-level workstation pick if AV1 encode or DisplayPort 2.1 output matter to your workflow; CUDA-dependent software users should still lean NVIDIA.
Frequently asked questions
Do the Instinct MI250 and Radeon PRO W7500 differ on board partner?
Yes. Board Partner reads Reference on the Instinct MI250 versus AMD Reference on the Radeon PRO W7500.
Is the GPU Brand the same on the Instinct MI250 and Radeon PRO W7500?
It is. Both are listed at AMD, so it is not a reason to pick one over the other.
Specs and benchmarks
GPU Brand
- AMD Instinct MI250
- AMD
- AMD Radeon PRO W7500
- AMD
Series
- AMD Instinct MI250
- Instinct
- AMD Radeon PRO W7500
- Radeon RX 7000
Board Partner
- AMD Instinct MI250
- Reference
- AMD Radeon PRO W7500
- AMD Reference
Tier
- AMD Instinct MI250
- Datacenter
- AMD Radeon PRO W7500
- Entry (Workstation)
Memory Type
- AMD Instinct MI250
- HBM2E
- AMD Radeon PRO W7500
- GDDR6Best
Boost Clock
- AMD Instinct MI250
- 1700 MHz-25%
- AMD Radeon PRO W7500
- 2260 MHzBest
TDP
- AMD Instinct MI250
- 500 W-614%
- AMD Radeon PRO W7500
- 70 WBest
Architecture
- AMD Instinct MI250
- CDNA2
- AMD Radeon PRO W7500
- RDNA 3
Slot Width
- AMD Instinct MI250
- Not Applicable
- AMD Radeon PRO W7500
- 1
Shader Units
- AMD Instinct MI250
- 13312
- AMD Radeon PRO W7500
- 1792
Compute Blocks
- AMD Instinct MI250
- 208
- AMD Radeon PRO W7500
- 28
Memory Bus Width
- AMD Instinct MI250
- 8192 bitBest
- AMD Radeon PRO W7500
- 128 bit-98%
PCIe Generation
- AMD Instinct MI250
- PCIe 4.0
- AMD Radeon PRO W7500
- PCIe 4.0 x8
Which one should you pick?
Choose AMD Instinct MI250 if you want the higher memory bus width (8192 bit vs 128 bit).
Choose AMD Radeon PRO W7500 if you want the higher boost clock (2260 MHz vs 1700 MHz) and the lower TDP (70 W vs 500 W).
Verdict
AMD Radeon PRO W7500
6.8 / 10 Expert Rating
A strong entry-level workstation pick if AV1 encode or DisplayPort 2.1 output matter to your workflow; CUDA-dependent software users should still lean NVIDIA.




