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AMD Instinct MI250 vs AMD Radeon R9 M275X: Comparison
Instinct MI250 vs Radeon R9 M275X memory bandwidth compared
The gap that matters here is memory bandwidth: Instinct MI250 3200 GB/s against Radeon R9 M275X 72 GB/s, which puts Instinct MI250 98% ahead. Instinct MI250 also leads on boost clock, 1700 MHz on the Instinct MI250 versus 925 MHz on the Radeon R9 M275X. Instinct MI250 also leads on memory bus width, 8192 bit on the Instinct MI250 versus 128 bit on the Radeon R9 M275X. Product type is not the same on both, Datacenter Accelerator on the Instinct MI250 versus Laptop GPU on the Radeon R9 M275X. They differ on board partner too, Reference on the Instinct MI250 versus AMD on the Radeon R9 M275X. Architecture is not the same on both, CDNA2 on the Instinct MI250 versus GCN on the Radeon R9 M275X. Shader units is not the same on both, 13312 on the Instinct MI250 versus 640 on the Radeon R9 M275X.
Who each one is for
The Instinct MI250 suits buyers comparing AMD's official reference specifications and researching a chip before choosing a board-partner card, though it is not built for overclocking-focused enthusiasts (reference clocks only). It is not the one for buyers wanting a specific retail card with cooler and warranty details. Buy the Radeon R9 M275X for buyers comparing AMD's official reference specifications and researching a chip before choosing a board-partner card, though it is not the pick for overclocking-focused enthusiasts (reference clocks only). It is the wrong buy for buyers wanting a specific retail card with cooler and warranty details.
Frequently asked questions
Do the Instinct MI250 and Radeon R9 M275X differ on vram capacity?
Yes. VRAM Capacity reads 128 GB on the Instinct MI250 versus 4 GB on the Radeon R9 M275X.
Is the GPU Brand the same on the Instinct MI250 and Radeon R9 M275X?
It is. Both are listed at AMD, so it is not a reason to pick one over the other.
Specs and benchmarks
GPU Brand
- AMD Instinct MI250
- AMD
- AMD Radeon R9 M275X
- AMD
Product Type
- AMD Instinct MI250
- Datacenter Accelerator
- AMD Radeon R9 M275X
- Laptop GPU
Series
- AMD Instinct MI250
- Instinct
- AMD Radeon R9 M275X
- Radeon R9 200 Series
Board Partner
- AMD Instinct MI250
- Reference
- AMD Radeon R9 M275X
- AMD (Reference)
Memory Type
- AMD Instinct MI250
- HBM2E
- AMD Radeon R9 M275X
- GDDR5Best
Boost Clock
- AMD Instinct MI250
- 1700 MHzBest
- AMD Radeon R9 M275X
- 925 MHz-46%
Architecture
- AMD Instinct MI250
- CDNA2
- AMD Radeon R9 M275X
- GCN
Process Node
- AMD Instinct MI250
- TSMC 6nm FinFET
- AMD Radeon R9 M275X
- Other
Shader Units
- AMD Instinct MI250
- 13312
- AMD Radeon R9 M275X
- 640
Compute Blocks
- AMD Instinct MI250
- 208
- AMD Radeon R9 M275X
- 10
VRAM Capacity
- AMD Instinct MI250
- 128 GBBest
- AMD Radeon R9 M275X
- 4 GB
Memory Bus Width
- AMD Instinct MI250
- 8192 bitBest
- AMD Radeon R9 M275X
- 128 bit-98%
Memory Bandwidth
- AMD Instinct MI250
- 3200 GB/sBest
- AMD Radeon R9 M275X
- 72 GB/s-98%
Launch Date
- AMD Instinct MI250
- 11/08/2021
- AMD Radeon R9 M275X
- January 2014
Form Factor
- AMD Instinct MI250
- OAM Module
- AMD Radeon R9 M275X
- Component
Which one should you pick?
Choose AMD Instinct MI250 if you want the higher boost clock (1700 MHz vs 925 MHz), the higher memory bus width (8192 bit vs 128 bit) and the higher memory bandwidth (3200 GB/s vs 72 GB/s).
Choose AMD Radeon R9 M275X if you already have it on hand or find it at a lower price.




