Consumercarts is reader-supported. Learn more
AMD Instinct MI250 vs AMD FirePro S4000X: Comparison
Instinct MI250 vs FirePro S4000X tdp compared
Start with tdp, because it is the widest measured gap between them: Instinct MI250 500 W against FirePro S4000X 45 W, 1011% in favour of FirePro S4000X. Memory bandwidth runs the same way, 3200 GB/s on the Instinct MI250 versus 72 GB/s on the FirePro S4000X, another win for Instinct MI250. They differ on architecture too, CDNA2 on the Instinct MI250 versus GCN on the FirePro S4000X. Shader units is not the same on both, 13312 on the Instinct MI250 versus 640 on the FirePro S4000X. There is a split on compute blocks as well, 208 on the Instinct MI250 versus 10 on the FirePro S4000X. They differ on pcie generation too, PCIe 4.0 on the Instinct MI250 versus PCIe 3.0 on the FirePro S4000X.
Which should you buy, Instinct MI250 or FirePro S4000X?
The Instinct MI250 is the one to take for buyers comparing AMD's official reference specifications and researching a chip before choosing a board-partner card, though it is not built for overclocking-focused enthusiasts (reference clocks only). It is the wrong buy for buyers wanting a specific retail card with cooler and warranty details. Buy the FirePro S4000X for buyers comparing AMD's official reference specifications and researching a chip before choosing a board-partner card, though it is the wrong buy for overclocking-focused enthusiasts (reference clocks only). It is not the one for buyers wanting a specific retail card with cooler and warranty details.
What Instinct MI250 and FirePro S4000X have in common
The common ground is wider than the gap: gpu brand, board partner, pcie lanes and cooling type are identical here.
Frequently asked questions
Do the Instinct MI250 and FirePro S4000X differ on vram capacity?
Yes. VRAM Capacity reads 128 GB on the Instinct MI250 versus 2 GB on the FirePro S4000X.
Specs and benchmarks
GPU Brand
- AMD Instinct MI250
- AMD
- AMD FirePro S4000X
- AMD
Series
- AMD Instinct MI250
- Instinct
- AMD FirePro S4000X
- Legacy
Board Partner
- AMD Instinct MI250
- Reference
- AMD FirePro S4000X
- Reference
Tier
- AMD Instinct MI250
- Datacenter
- AMD FirePro S4000X
- Workstation
Memory Type
- AMD Instinct MI250
- HBM2E
- AMD FirePro S4000X
- GDDR5Best
TDP
- AMD Instinct MI250
- 500 W-1011%
- AMD FirePro S4000X
- 45 WBest
Architecture
- AMD Instinct MI250
- CDNA2
- AMD FirePro S4000X
- GCN
Process Node
- AMD Instinct MI250
- TSMC 6nm FinFET
- AMD FirePro S4000X
- Other
Shader Units
- AMD Instinct MI250
- 13312
- AMD FirePro S4000X
- 640
Compute Blocks
- AMD Instinct MI250
- 208
- AMD FirePro S4000X
- 10
VRAM Capacity
- AMD Instinct MI250
- 128 GBBest
- AMD FirePro S4000X
- 2 GB
Memory Bandwidth
- AMD Instinct MI250
- 3200 GB/sBest
- AMD FirePro S4000X
- 72 GB/s-98%
PCIe Generation
- AMD Instinct MI250
- PCIe 4.0
- AMD FirePro S4000X
- PCIe 3.0
PCIe Lanes
- AMD Instinct MI250
- 16
- AMD FirePro S4000X
- 16
Cooling Type
- AMD Instinct MI250
- Passive
- AMD FirePro S4000X
- Passive
Launch Date
- AMD Instinct MI250
- 11/08/2021
- AMD FirePro S4000X
- August 2014
ECC Memory
- AMD Instinct MI250
- Yes
- AMD FirePro S4000X
- No
Form Factor
- AMD Instinct MI250
- OAM Module
- AMD FirePro S4000X
- Servers
Which one should you pick?
Choose AMD Instinct MI250 if you want the higher memory bandwidth (3200 GB/s vs 72 GB/s) and the higher PCIe lanes (16 vs 16).
Choose AMD FirePro S4000X if you want the lower TDP (45 W vs 500 W).