Consumercarts is reader-supported. Learn more
AMD Instinct MI250 vs AMD FirePro W4300: Comparison
Instinct MI250 vs FirePro W4300 tdp compared
On tdp the spread is 900%, Instinct MI250 500 W against FirePro W4300 50 W, so FirePro W4300 takes it. Add memory bandwidth to that, 3200 GB/s on the Instinct MI250 versus 96 GB/s on the FirePro W4300, and the pattern holds. Boost clock runs the same way, 1700 MHz on the Instinct MI250 versus 930 MHz on the FirePro W4300, another win for Instinct MI250. Instinct MI250 also leads on memory bus width, 8192 bit on the Instinct MI250 versus 128 bit on the FirePro W4300. They differ on product type too, Datacenter Accelerator on the Instinct MI250 versus Workstation Card on the FirePro W4300. There is a split on tier as well, Datacenter on the Instinct MI250 versus Workstation on the FirePro W4300. On memory type there is little in it, HBM2E on the Instinct MI250 versus GDDR5 on the FirePro W4300. Architecture is not the same on both, CDNA2 on the Instinct MI250 versus GCN on the FirePro W4300. They differ on shader units too, 13312 on the Instinct MI250 versus 768 on the FirePro W4300.
Instinct MI250 vs FirePro W4300: which one fits your build
The Instinct MI250 suits buyers comparing AMD's official reference specifications and researching a chip before choosing a board-partner card, though it is not the pick for overclocking-focused enthusiasts (reference clocks only). It is not the one for buyers wanting a specific retail card with cooler and warranty details. Buy the FirePro W4300 for buyers comparing AMD's official reference specifications and researching a chip before choosing a board-partner card, though it is the wrong buy for overclocking-focused enthusiasts (reference clocks only). It is the wrong buy for buyers wanting a specific retail card with cooler and warranty details.
Where the two are identical
Everything else lines up. Gpu brand, board partner and pcie lanes read the same on both, so those are not worth weighing.
Frequently asked questions
Do the Instinct MI250 and FirePro W4300 differ on pcie generation?
Yes. PCIe Generation reads PCIe 4.0 on the Instinct MI250 versus PCIe 3.0 on the FirePro W4300.
Specs and benchmarks
GPU Brand
- AMD Instinct MI250
- AMD
- AMD FirePro W4300
- AMD
Product Type
- AMD Instinct MI250
- Datacenter Accelerator
- AMD FirePro W4300
- Workstation Card
Series
- AMD Instinct MI250
- Instinct
- AMD FirePro W4300
- Legacy
Board Partner
- AMD Instinct MI250
- Reference
- AMD FirePro W4300
- Reference
Tier
- AMD Instinct MI250
- Datacenter
- AMD FirePro W4300
- Workstation
Memory Type
- AMD Instinct MI250
- HBM2E
- AMD FirePro W4300
- GDDR5Best
Boost Clock
- AMD Instinct MI250
- 1700 MHzBest
- AMD FirePro W4300
- 930 MHz-45%
TDP
- AMD Instinct MI250
- 500 W-900%
- AMD FirePro W4300
- 50 WBest
Architecture
- AMD Instinct MI250
- CDNA2
- AMD FirePro W4300
- GCN
Shader Units
- AMD Instinct MI250
- 13312
- AMD FirePro W4300
- 768
Memory Bus Width
- AMD Instinct MI250
- 8192 bitBest
- AMD FirePro W4300
- 128 bit-98%
Memory Bandwidth
- AMD Instinct MI250
- 3200 GB/sBest
- AMD FirePro W4300
- 96 GB/s-97%
PCIe Generation
- AMD Instinct MI250
- PCIe 4.0
- AMD FirePro W4300
- PCIe 3.0
PCIe Lanes
- AMD Instinct MI250
- 16
- AMD FirePro W4300
- 16
Launch Date
- AMD Instinct MI250
- 11/08/2021
- AMD FirePro W4300
- December 2015
ECC Memory
- AMD Instinct MI250
- Yes
- AMD FirePro W4300
- No
Form Factor
- AMD Instinct MI250
- OAM Module
- AMD FirePro W4300
- Desktops
Which one should you pick?
Choose AMD Instinct MI250 if you want the higher boost clock (1700 MHz vs 930 MHz), the higher memory bus width (8192 bit vs 128 bit) and the higher memory bandwidth (3200 GB/s vs 96 GB/s).
Choose AMD FirePro W4300 if you want the lower TDP (50 W vs 500 W).




