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AMD Instinct MI250 vs NVIDIA GeForce RTX 4060 Ti 16GB: Comparison
AMD Instinct MI250 vs NVIDIA GeForce RTX 4060 Ti 16GB tdp compared
The gap that matters here is tdp: AMD Instinct MI250 500 W against NVIDIA GeForce RTX 4060 Ti 16GB 165 W, which puts NVIDIA GeForce RTX 4060 Ti 16GB 203% ahead. AMD Instinct MI250 also leads on memory bus width, 8192 bit on the AMD Instinct MI250 versus 128 bit on the NVIDIA GeForce RTX 4060 Ti 16GB. NVIDIA GeForce RTX 4060 Ti 16GB also leads on boost clock, 1700 MHz on the AMD Instinct MI250 versus 2535 MHz on the NVIDIA GeForce RTX 4060 Ti 16GB. Architecture is not the same on both, CDNA2 on the AMD Instinct MI250 versus Ada Lovelace on the NVIDIA GeForce RTX 4060 Ti 16GB. They differ on shader units too, 13312 on the AMD Instinct MI250 versus 4352 on the NVIDIA GeForce RTX 4060 Ti 16GB.
Which should you buy, AMD Instinct MI250 or NVIDIA GeForce RTX 4060 Ti 16GB?
Buy the AMD Instinct MI250 for buyers comparing AMD's official reference specifications and researching a chip before choosing a board-partner card, though it is the wrong buy for overclocking-focused enthusiasts (reference clocks only). It is the wrong buy for buyers wanting a specific retail card with cooler and warranty details. it is not built for buyers on a strict budget who only game at 1080p. It is equally the pick for 1440p gaming and light local AI workloads where 8GB feels tight. Our rating of the NVIDIA GeForce RTX 4060 Ti 16GB (7.5/10): the same AD106 core as the 8GB card with double the memory, which matters most for modded games and light local AI work.
Frequently asked questions
Do the AMD Instinct MI250 and NVIDIA GeForce RTX 4060 Ti 16GB differ on gpu brand?
Yes. GPU Brand reads AMD on the AMD Instinct MI250 versus NVIDIA on the NVIDIA GeForce RTX 4060 Ti 16GB.
Specs and benchmarks
GPU Brand
- AMD Instinct MI250
- AMD
- NVIDIA GeForce RTX 4060 Ti 16GB
- NVIDIA
Tier
- AMD Instinct MI250
- Datacenter
- NVIDIA GeForce RTX 4060 Ti 16GB
- Mainstream
Memory Type
- AMD Instinct MI250
- HBM2E
- NVIDIA GeForce RTX 4060 Ti 16GB
- GDDR6Best
Boost Clock
- AMD Instinct MI250
- 1700 MHz-33%
- NVIDIA GeForce RTX 4060 Ti 16GB
- 2535 MHzBest
TDP
- AMD Instinct MI250
- 500 W-203%
- NVIDIA GeForce RTX 4060 Ti 16GB
- 165 WBest
Architecture
- AMD Instinct MI250
- CDNA2
- NVIDIA GeForce RTX 4060 Ti 16GB
- Ada Lovelace (AD106)
Shader Units
- AMD Instinct MI250
- 13312
- NVIDIA GeForce RTX 4060 Ti 16GB
- 4352
Memory Bus Width
- AMD Instinct MI250
- 8192 bitBest
- NVIDIA GeForce RTX 4060 Ti 16GB
- 128 bit-98%
Which one should you pick?
Choose AMD Instinct MI250 if you want the higher memory bus width (8192 bit vs 128 bit).
Choose NVIDIA GeForce RTX 4060 Ti 16GB if you want the higher boost clock (2535 MHz vs 1700 MHz) and the lower TDP (165 W vs 500 W).
Price comparison
| Retailer | AMD Instinct MI250 | NVIDIA GeForce RTX 4060 Ti 16GB |
|---|---|---|
| Consumercarts listing | $499.00 View on Consumercarts listing |
Disclaimer: The price and specification of the given product may differ from the actual product. Please confirm on the retailer's website before buying.
Verdict
NVIDIA GeForce RTX 4060 Ti 16GB
7.5 / 10 Expert Rating
The same AD106 core as the 8GB card with double the memory, which matters most for modded games and light local AI work.




