Consumercarts is reader-supported. Learn more
AMD Instinct MI250 vs NVIDIA GeForce RTX 4080 Super: Comparison
What is the difference between AMD Instinct MI250 and NVIDIA GeForce RTX 4080 Super?
Memory bandwidth is where these two genuinely part company, AMD Instinct MI250 3200 GB/s against NVIDIA GeForce RTX 4080 Super 736 GB/s, a 77% lead for AMD Instinct MI250. NVIDIA GeForce RTX 4080 Super also leads on tdp, 500 W on the AMD Instinct MI250 versus 320 W on the NVIDIA GeForce RTX 4080 Super. Memory bus width runs the same way, 8192 bit on the AMD Instinct MI250 versus 256 bit on the NVIDIA GeForce RTX 4080 Super, another win for AMD Instinct MI250. Add boost clock to that, 1700 MHz on the AMD Instinct MI250 versus 2550 MHz on the NVIDIA GeForce RTX 4080 Super, and the pattern holds. They differ on shader units too, 13312 on the AMD Instinct MI250 versus 10240 on the NVIDIA GeForce RTX 4080 Super.
Which should you buy, AMD Instinct MI250 or NVIDIA GeForce RTX 4080 Super?
The AMD Instinct MI250 is the one to take for buyers comparing AMD's official reference specifications and researching a chip before choosing a board-partner card, though it is not the pick for overclocking-focused enthusiasts (reference clocks only). It is the wrong buy for buyers wanting a specific retail card with cooler and warranty details. Buy the NVIDIA GeForce RTX 4080 Super for enthusiasts who want near-flagship 4K performance without RTX 4090 pricing, though it is not built for buyers chasing the absolute highest benchmark numbers regardless of cost. Our rating of the NVIDIA GeForce RTX 4080 Super (8.5/10): near-flagship 4K performance at a $200 price correction over the card it replaced.
Frequently asked questions
Do the AMD Instinct MI250 and NVIDIA GeForce RTX 4080 Super differ on gpu brand?
Yes. GPU Brand reads AMD on the AMD Instinct MI250 versus NVIDIA on the NVIDIA GeForce RTX 4080 Super.
Specs and benchmarks
GPU Brand
- AMD Instinct MI250
- AMD
- NVIDIA GeForce RTX 4080 Super
- NVIDIA
Tier
- AMD Instinct MI250
- Datacenter
- NVIDIA GeForce RTX 4080 Super
- High End
Memory Type
- AMD Instinct MI250
- HBM2E
- NVIDIA GeForce RTX 4080 Super
- GDDR6XBest
Boost Clock
- AMD Instinct MI250
- 1700 MHz-33%
- NVIDIA GeForce RTX 4080 Super
- 2550 MHzBest
TDP
- AMD Instinct MI250
- 500 W-56%
- NVIDIA GeForce RTX 4080 Super
- 320 WBest
Architecture
- AMD Instinct MI250
- CDNA2
- NVIDIA GeForce RTX 4080 Super
- Ada Lovelace (AD103)
Shader Units
- AMD Instinct MI250
- 13312
- NVIDIA GeForce RTX 4080 Super
- 10240
Memory Bus Width
- AMD Instinct MI250
- 8192 bitBest
- NVIDIA GeForce RTX 4080 Super
- 256 bit-97%
Memory Bandwidth
- AMD Instinct MI250
- 3200 GB/sBest
- NVIDIA GeForce RTX 4080 Super
- 736 GB/s-77%
Which one should you pick?
Choose AMD Instinct MI250 if you want the higher memory bus width (8192 bit vs 256 bit) and the higher memory bandwidth (3200 GB/s vs 736 GB/s).
Choose NVIDIA GeForce RTX 4080 Super if you want the higher boost clock (2550 MHz vs 1700 MHz) and the lower TDP (320 W vs 500 W).
Price comparison
| Retailer | AMD Instinct MI250 | NVIDIA GeForce RTX 4080 Super |
|---|---|---|
| Consumercarts listing | $999.00 View on Consumercarts listing |
Disclaimer: The price and specification of the given product may differ from the actual product. Please confirm on the retailer's website before buying.
Verdict
NVIDIA GeForce RTX 4080 Super
8.5 / 10 Expert Rating
Near-flagship 4K performance at a $200 price correction over the card it replaced.




